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Cell variability inside categories

When a cell which belongs to a given cell category is created, the values of the baseline parameters of the cell, and the factor relevance coefficients are generated from the values of the cell category.

Nevertheless, current arrhythmogenic theories sometimes rely on inhomogeneities of the cardiac tissue. For example, it is known that the vagus nerve does not inervate all regions of the atria, or even of the sinus node the same. It would be counterproductive to describe an imaginary pattern of changes by means of a large number of cell categories. Thus we provided a mechanism to specify variability of basic parameters and relevance coefficients.

In the categories, one may specify every parameter or coefficient to have a fixed numeric value, in which case it will have that value for every cell in the category.

One may specify a parameter or coefficient a most probable value and a range of variation towards more or less, like this: 300 plus 50 minus 10 to tell for example that phase 2 of the action potential of a category of cells is typically 300 but may be as much as 350 and as little as 290. For every cell in the category, CLARRHMOS will generate a value inside the range.


next up previous
Next: The anatomic model Up: The cord model Previous: Calculation of factor effect